04 May 2010 ~ Comments Off on Impact of race and ethnicity on ischemic stroke. The University of California at San Diego Stroke Data Bank

Impact of race and ethnicity on ischemic stroke. The University of California at San Diego Stroke Data Bank

BACKGROUND AND PURPOSE: As the US minority population continues to grow, increasing numbers of nonwhite citizens are at risk for stroke. A better understanding of how ischemic stroke differs in the minority populations may lead to more effective clinical management. METHODS: We prospectively evaluated 542 consecutive patients (416 whites, 71 Mexican Americans, 55 blacks) presenting […]

Continue Reading

04 May 2010 ~ Comments Off on Prognostic value of plasma HER-2/neu in African American and Hispanic women with breast cancer

Prognostic value of plasma HER-2/neu in African American and Hispanic women with breast cancer

We examined the significance of plasma HER-2/neu as a clinical or biological marker for assessing the progression of breast cancer in African American and Hispanic women with similar socioeconomic status, similar health insurance, and similar access to health care delivery. Base line studies show the following: average age of our breast cancer patients was 48 […]

Continue Reading

04 May 2010 ~ Comments Off on Disparate outcomes in patients with colorectal cancer: effect of race on long-term survival

Disparate outcomes in patients with colorectal cancer: effect of race on long-term survival

BACKGROUND: Increasing evidence suggests significant disparity in colorectal cancer outcomes between black and white patients. Contributing factors may include advanced tumor stage at diagnosis, differences in treatment, more aggressive tumor biology, access to care, and patient comorbidity. HYPOTHESIS: Disparities in colorectal cancer outcomes exist despite similar objective measures of treatment. DESIGN AND SETTING: Ten-year retrospective […]

Continue Reading

04 May 2010 ~ Comments Off on The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT): clinical center recruitment experience

The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT): clinical center recruitment experience

The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) is a randomized clinical outcome trial of antihypertensive and lipid-lowering therapy in a diverse population (including substantial numbers of women and minorities) of 42,419 high-risk hypertensives aged > or = 55 years with a planned mean follow-up of 6 years. In this paper, we […]

Continue Reading

04 May 2010 ~ Comments Off on Contribution of major diseases to disparities in mortality

Contribution of major diseases to disparities in mortality

BACKGROUND: Mortality from all causes is higher for persons with fewer years of education and for blacks, but it is unknown which diseases contribute most to these disparities. METHODS: We estimated cause-specific risks of death from data from the National Health Interview Survey conducted from 1986 through 1994 and from linked vital statistics. Using these […]

Continue Reading

04 May 2010 ~ Comments Off on Cancer prevention in underserved African American communities: barriers and effective strategies–a review of the literature

Cancer prevention in underserved African American communities: barriers and effective strategies–a review of the literature

African Americans suffer significantly more cancer morbidity and mortality than the white population. In order to decrease this differential, it is critical to understand the particular barriers to health and health care that underserved African Americans face. It is also important to identify the critical components of effective cancer prevention programs for this population. The […]

Continue Reading

04 May 2010 ~ Comments Off on Confronting racial disparities in infant mortality: reconciling science and politics

Confronting racial disparities in infant mortality: reconciling science and politics

The public debate surrounding disparities in infant mortality has resulted from a profound failure to seek a common wisdom. Because of its essential social roots, infant mortality will always remain the province of fundamental ideological and political conflict. However, without a more integrated analytic approach, progress in reducing disparate infant mortality will remain limited by […]

Continue Reading

04 May 2010 ~ Comments Off on Racial disparities in cardiovascular health care: unfulfilled exSPECTations?[comment]

Racial disparities in cardiovascular health care: unfulfilled exSPECTations?[comment]

Continue Reading

04 May 2010 ~ Comments Off on Racial differences in the use of invasive cardiovascular procedures in the Department of Veterans Affairs medical system.[see comment]

Racial differences in the use of invasive cardiovascular procedures in the Department of Veterans Affairs medical system.[see comment]

BACKGROUND. Previous studies have found racial differences in the use of invasive cardiovascular procedures, which may be due in part to the greater financial incentives to perform such procedures in white patients. In Department of Veterans Affairs hospitals, direct financial incentives affecting use of the procedures are minimized for both patients and physicians. METHODS. We […]

Continue Reading

04 May 2010 ~ Comments Off on Comorbidity and breast cancer survival: a comparison between black and white women

Comorbidity and breast cancer survival: a comparison between black and white women

The presence of concurrent health conditions (comorbidity) at the time of breast cancer diagnosis has an adverse effect on survival. It is unclear, however, whether the strength of the association between comorbidity and survival varies in different populations of breast cancer patients. It is necessary, therefore, to establish (1) whether a comorbidity index derived from […]

Continue Reading